Homocysteine Plus is an updated version of our original Homocysteine Metabolite Formula. It provides the primary nutrients known to be necessary for the breakdown of homocysteine into methionine and other metabolites, including vitamin B6 as pyridoxine and pyridoxal-5’-phosphate (P5P), vitamin B12 as methylcobalamin, folate as 5-methyltetrahydrofolate (5-MTHF), trimethylglycine (TMG), and L-serine. It is now enhanced with vitamin B2 as riboflavin-5-phosphate, Setria® glutathione, zinc, and increased amounts of activated pyridoxal-5’-phosphate.

Normal homocysteine levels have been associated with cardiovascular and cognitive health, normal metabolism, and a healthy mood. Homocysteine may affect all other methyl and sulphur group metabolism processes either directly or indirectly.

Homocysteine is metabolised from the essential amino acid methionine. To prevent excess homocysteine accumulation, the body can degrade it through two pathways of liver detoxification, transsulphuration and remethylation. The transsulphuration pathway requires both pyridoxine and P5P as well as serine, and the remethylation pathway can involve methylcobalamin (the active form of B12), S-adenosyl-methionine (SAMe),5-methyltetrahydrofolate, zinc, and trimethylglycine.

Serving Instructions

As a dietary supplement, 1 capsule one or two times daily with meals, or as directed by a healthcare practitioner.

Serving Size

1 capsule contains:

Ingredients

Vitamin B2 (as Riboflavin-5-Phosphate)  10 mg
Vitamin B6 (50% as Pyridoxine Hydrochloride and 50% as Pyridoxal-5-Phosphate)  30 mg
Folate (as 400 µg of 5-Methyltetrahydrofolate (from 740 µg [6S]-5-methyltetrahydrofolate acid, glucosamine salt))  667 µgDFE
Vitamin B12 (as Methylcobalamin)  400 µg
Zinc Picolinate  5 mg
Trimethylglycine  500 mg
L-Serine  100 mg
L-Glutathione (reduced)  50 mg

Other Ingredients

: 
Hydroxypropyl methylcellulose 

Magnesium stearate
Microcrystalline cellulose
Silicon dioxide